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Sin embargo, en determinados pacientes no se logra un control analgésico adecuado, a pesar de utilizar dosis elevadas, o bien aparecen efectos secundarios intolerables antes de conseguir un grado efectivo de analgesia.2012; Childress et al. 2019). The onset of motion occurs approximately 30 to 45 minutes just after consumption, depending on the in

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